We are pleased to announce the release of PASS 2008. This edition of PASS has been split from NCSS and now functions as an independent application. PASS 2008 adds over 40 new power and sample size procedures and features to PASS, including procedures for mixed models, kappa testing, Normality testing, Cochran-Armitage proportion trend testing, new survival analysis procedures, tools to create randomization lists, several confidence interval procedures, several design of experiments procedures, microarray gene expression comparison tools, an enhanced user interface, an improved help system, and the ability to create macros (which add programmability and streamline repeated tasks).

All templates from previous versions of PASS are fully compatible with PASS 2008.

PASS 2008 is fully compatible with Windows Vista.

New Procedures
Mixed Models
Logrank (Survival) Tests
Logrank Non-Inferiority Tests
Randomization Lists
Kappa Test for Agreement Between Two Raters
Confidence Intervals - Means (6 Procedures)
Confidence Intervals - Proportions (2 Procedures)
Confidence Intervals - Regression Slope
Confidence Intervals - SD/Variance (8 Procedures)
Confidence Intervals - Correlation
Microarray One-Sample/Paired T-Tests
Microarray Two-Sample T-Tests
Cochran-Armitage Proportion Trend Tests
Normality Tests
Longitudinal Time-Averaged Differencing - Two Means
Longitudinal Time-Averaged Differencing - Two Proportions
Design of Experiments (9 Procedures)

New Features
Simplified Interface
Improved Help System
Quick Launch
Macros (Programmability)

Prices
Upgrade from PASS 2005:
$349.95 (academic/government)
$399.95 (commercial)

Upgrade from Earlier Versions:
$449.95 (academic/government)
$499.95 (commercial)

Click here to view complete price lists.

Ordering
To order your upgrade, call us at 1-800-898-6109 (US only) or (801) 546-0445, fax us at (801) 546-3907, email us at sales@ncss.com, or order from our secure online order form.

Documentation
PDF versions of the documentation are available directly from each procedure window. These may be displayed or printed. The documentation is also available in the help system. You can purchase a printed copy of the three manuals for $100.

Mixed Models
The new Mixed Models procedure uses simulation to power analyze a variety of experimental designs for comparing means in which the response is continuous. The procedure focuses on models that are commonly used to analyze longitudinal (repeated measures) data, but can also be used to determine power for split-plot designs, cross-over designs, factorial designs, etc.

Logrank Tests
Five new logrank test procedures greatly improve the accuracy and ability to compute the sample size and power of the logrank test for equality or non-inferiority of survival distributions under very general assumptions. Accrual time, follow-up time, loss during follow-up, noncompliance, and hazard rates may vary with time. The parameterization can be in terms of hazard rates, median survival time, proportion surviving, or mortality.

Randomization Lists
This procedure creates randomization lists for assigning subjects to one of up to eight treatments. Six randomization algorithms are available. Four of the algorithms (Efron’s biased coin randomization, Smith’s randomization, Wei’s urn randomization, and random sorting using maximum allowable % deviation) are designed to generate balanced random samples throughout the course of an experiment. The other two (complete randomization and random sorting) are less complex but have higher probabilities of imbalance. 

Kappa Test for Agreement Between Two Raters
This procedure computes power and sample size for the test of agreement between two raters using the kappa statistic. Calculations are based on ratings for k categories from two raters or judges. You are able to vary category frequencies on a single run to analyze a wide range of scenarios at once.

Confidence Intervals
Eighteen new confidence interval procedures have been added to PASS 2008. These procedures cover confidence intervals for one mean, two means, one standard deviation, one variance, two variances, one proportion, two proportions, regression slope, and one correlation. In some procedures tolerance probabilities or relative error may additionally be specified.

Microarray T-Tests (One- or Two-sample, Paired)
Two new microarray procedures estimate the power and number of arrays required for one-sample, two-sample, and paired sample t-tests of microarray gene expression data. False discovery rate and experiment-wise error rate control methods are available in this procedure.

Cochran-Armitage Proportion Trend Test
This procedure computes power and sample size for the Cochran-Armitage test for a linear trend in proportions. Asymptotic and exact power calculations for the uncorrected and continuity-corrected tests are available.

Normality Tests
This procedure uses simulation to determine the power of eight normality tests (Anderson-Darling, Kolmogorov-Smirnov, Kurtosis, Martinez-Iglewicz, Omnibus, Range/SD, Shapiro-Wilk, and Skewness). A wide variety of alternative distributions can be specified in this procedure.

Longitudinal Time-Averaged Differencing - Two Means/Proportions
Two new time-averaged differencing procedures calculate the power for testing the time-averaged difference between two means or two proportions in a longitudinal design. The data from such a design are often analyzed using mixed models software. Measurements may be taken at pre-determined times or at random times.

Design of Experiments
Nine new experimental design procedures have been added to PASS 2008. The procedures generate designs based on the number of desired factors and desired number of levels of each factor. The experimental design procedures are Two-Level, Fractional Factorial, Balanced incomplete Block, Latin Square, Response Surface, Screening, Taguchi, D-Optimal, and the Design Generator.

Simplified Interface
The interface has been redesigned to make the user input easier to complete. Boxes containing descriptive titles have been added to group similar options. This allows for easier navigation of the procedure windows and faster identification of input categories. Input boxes have also been made to gray out when inactive.

Improved Help System
The PASS Help System has been designed for easier searching and printing. Chapter and keyword indices have been added, and the entire Help System is now searchable. Individual PDF chapters can be printed as well as whole sections of the manuals.

Quick Launch
The Quick Launch window contains a button corresponding to each procedure in the system. The Quick Launch window makes it easy to find and launch any procedure.

Macros (Programmability)
The Macros feature utilizes a batch language that lets you create and run macros (scripts/programs) for repeated tasks. With the click of a single button, the program will run a series of procedures.

Buy the PASS 2008 Upgrade now